Bioscience for Health

Delivery of Raman active nanoparticles to dopaminergic neurons to investigate age-related protein aggregation

Supervisors: Prof. Alison Hulme, Dr Tilo Kunath, Dr Mathew Horrocks

Project Description:

This project will investigate age-associated protein aggregation within neurons using Raman active ‘loaded’ nanoparticles delivered both to human dopaminergic neurons in culture, and into the brain of a genetic rat model that has α-synuclein aggregation.