Below is a list of all EASTBIO student/alumni publications, by year of publication:


Benek, O., L. Hroch, L. Aitken, R. Dolezal, P. Guest, M. Benkova, O. Soukup, K. Musil, K. Kuca, T. K. Smith, F. Gunn-Moore and K. Musilek (2017). ‘6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17beta-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.’ Med Chem.

Davies, F. C., J. E. Hope, F. McLachlan, F. Nunez, J. Doig, H. Bengani, C. Smith and C. M. Abbott (2017). ‘Biallelic mutations in the gene encoding eEF1A2 cause seizures and sudden death in F0 mice.’ Sci Rep 7: 46019.

Giotti, B., A. Joshi and T. C. Freeman (2017). ‘Meta-analysis reveals conserved cell cycle transcriptional network across multiple human cell types.’ BMC Genomics 18(1): 30.

Glendinning, L., S. Wright, P. Tennant, A. C. Gill, D. Collie and G. McLachlan (2017). ‘Microbiota in Exhaled Breath Condensate and the Lung.’ Appl Environ Microbiol.

Heath, S. E., K. Knox, P. F. Vale and S. Collins (2017). ‘Virus Resistance Is Not Costly in a Marine Alga Evolving under Multiple Environmental Stressors.’ Viruses 9(3).

Hroch, L., P. Guest, O. Benek, O. Soukup, J. Janockova, R. Dolezal, K. Kuca, L. Aitken, T. K. Smith, F. Gunn-Moore, D. Zala, R. R. Ramsay and K. Musilek (2017). ‘Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.’ Bioorg Med Chem 25(3): 1143-1152.

Lamont, C. M. and F. Sargent (2017). ‘Design and characterisation of synthetic operons for biohydrogen technology.’ Arch Microbiol 199(3): 495-503.

Picton, L. D., F. Nascimento, M. J. Broadhead, K. T. Sillar and G. B. Miles (2017). ‘Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks.’ J Neurosci 37(4): 906-921.

Smith, S. and R. Grima (2017). ‘Fast simulation of Brownian dynamics in a crowded environment.’ J Chem Phys 146(2): 024105.

Voss, J. J., C. A. Ford, S. Petrova, L. Melville, M. Paterson, J. D. Pound, P. Holland, B. Giotti, T. C. Freeman and C. D. Gregory (2017). ‘Modulation of macrophage antitumor potential by apoptotic lymphoma cells.’ Cell Death Differ.


Ait-Ali, T., I. Diaz, F. Soldevila, E. Cano, Y. Li, A. D. Wilson, B. Giotti, A. L. Archibald, E. Mateu and L. Darwich (2016). ‘Distinct functional enrichment of transcriptional signatures in pigs with high and low IFN-gamma responses after vaccination with a porcine reproductive and respiratory syndrome virus (PRRSV).’ Vet Res 47(1): 104.

Brewster, R. C., G. C. Gavins, B. Gunthardt, S. Farr, K. M. Webb, P. Voigt and A. N. Hulme (2016). ‘Chloromethyl-triazole: a new motif for site-selective pseudo-acylation of proteins.’ Chem Commun (Camb) 52(82): 12230-12232.

Christensen, L. L., C. Selman, J. D. Blount, J. G. Pilkington, K. A. Watt, J. M. Pemberton, J. M. Reid and D. H. Nussey (2016). ‘Marker-dependent associations among oxidative stress, growth and survival during early life in a wild mammal.’ Proc Biol Sci 283(1840).

Christensen, L. L., K. True, M. P. Hamilton, M. M. Nielsen, N. D. Damas, C. K. Damgaard, H. Ongen, E. Dermitzakis, J. B. Bramsen, J. S. Pedersen, A. H. Lund, S. Vang, K. Stribolt, M. R. Madsen, S. Laurberg, S. E. McGuire, T. F. Orntoft and C. L. Andersen (2016). ‘SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism.’ Mol Oncol 10(8): 1266-1282.

Cianci, C., S. Smith and R. Grima (2016). ‘Molecular finite-size effects in stochastic models of equilibrium chemical systems.’ J Chem Phys 144(8): 084101.

Coakley, G., A. H. Buck and R. M. Maizels (2016). ‘Host parasite communications-Messages from helminths for the immune system: Parasite communication and cell-cell interactions.’ Mol Biochem Parasitol 208(1): 33-40.

Cui, L., D. A. Houston, C. Farquharson and V. E. MacRae (2016). ‘Characterisation of matrix vesicles in skeletal and soft tissue mineralisation.’ Bone 87: 147-158.

Custodio, R., C. J. McLean, A. E. Scott, J. Lowther, A. Kennedy, D. J. Clarke, D. J. Campopiano, M. Sarkar-Tyson and A. R. Brown (2016). ‘Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei.’ Mol Microbiol 102(6): 1004-1019.

Donaldson, D. S., A. Sehgal, D. Rios, I. R. Williams and N. A. Mabbott (2016). ‘Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility.’ PLoS Pathog 12(12): e1006075.

Glendinning, L., S. Wright, J. Pollock, P. Tennant, D. Collie and G. McLachlan (2016). ‘Variability of the Sheep Lung Microbiota.’ Appl Environ Microbiol 82(11): 3225-3238.

Gorgoni, B., L. Ciandrini, M. R. McFarland, M. C. Romano and I. Stansfield (2016). ‘Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translation.’ Nucleic Acids Res 44(19): 9231-9244.

Heath, S. E. and S. Collins (2016). ‘Mode of resistance to viral lysis affects host growth across multiple environments in the marine picoeukaryote Ostreococcus tauri.’ Environ Microbiol 18(12): 4628-4639.

Houston, D. A., K. Myers, V. E. MacRae, K. A. Staines and C. Farquharson (2016). ‘The Expression of PHOSPHO1, nSMase2 and TNAP is Coordinately Regulated by Continuous PTH Exposure in Mineralising Osteoblast Cultures.’ Calcif Tissue Int 99(5): 510-524.

Houston, D. A., K. A. Staines, V. E. MacRae and C. Farquharson (2016). ‘Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification.’ J Vis Exp(118).

Jager, F., M. Zoltner, H. Kneuper, W. N. Hunter and T. Palmer (2016). ‘Membrane interactions and self-association of components of the Ess/Type VII secretion system of Staphylococcus aureus.’ FEBS Lett 590(3): 349-357.

Moatt, J. P., S. Nakagawa, M. Lagisz and C. A. Walling (2016). ‘The effect of dietary restriction on reproduction: a meta-analytic perspective.’ BMC Evol Biol 16(1): 199.

Sillar, K.T., Picton, L.P. & Heitler, W.J. (2016) The Neuroethology of Predation and Escape. 392 pp. Wiley-Blackwell.

Simbari, F., J. McCaskill, G. Coakley, M. Millar, R. M. Maizels, G. Fabrias, J. Casas and A. H. Buck (2016). ‘Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications for exosome stability and biology.’ J Extracell Vesicles 5: 30741.

Smith, S., C. Cianci and R. Grima (2016). ‘Analytical approximations for spatial stochastic gene expression in single cells and tissues.’ J R Soc Interface 13(118).

Smith, S. and R. Grima (2016). ‘Breakdown of the reaction-diffusion master equation with nonelementary rates.’ Phys Rev E 93(5): 052135.

Souilhol, C., J. G. Lendinez, S. Rybtsov, F. Murphy, H. Wilson, D. Hills, A. Batsivari, A. Binagui-Casas, A. C. McGarvey, H. R. MacDonald, R. Kageyama, C. Siebel, S. Zhao and A. Medvinsky (2016). ‘Developing HSCs become Notch independent by the end of maturation in the AGM region.’ Blood 128(12): 1567-1577.

Speakman, J. R., J. D. Blount, A. M. Bronikowski, R. Buffenstein, C. Isaksson, T. B. Kirkwood, P. Monaghan, S. E. Ozanne, M. Beaulieu, M. Briga, S. K. Carr, L. L. Christensen, H. M. Cocheme, D. L. Cram, B. Dantzer, J. M. Harper, D. Jurk, A. King, J. C. Noguera, K. Salin, E. Sild, M. J. Simons, S. Smith, A. Stier, M. Tobler, E. Vitikainen, M. Peaker and C. Selman (2015). ‘Oxidative stress and life histories: unresolved issues and current needs.’ Ecol Evol 5(24): 5745-5757.

Tsang, H. G., N. A. Rashdan, C. B. Whitelaw, B. M. Corcoran, K. M. Summers and V. E. MacRae (2016). ‘Large animal models of cardiovascular disease.’ Cell Biochem Funct 34(3): 113-132.

Tuck, L. R., Altenbach, K., Ang, T. F., Crawshaw, A. D., Campopiano, D. J., Clarke, D. J. and Marles-Wright, J. (2016). ‘Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans.’ Sci Rep 6: 22108.

Watson, R. L., T. N. McNeilly, K. A. Watt, J. M. Pemberton, J. G. Pilkington, M. Waterfall, P. R. Hopper, D. Cooney, R. Zamoyska and D. H. Nussey (2016). ‘Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival.’ Ecol Evol 6(24): 8695-8705.


Buck, A. H., G. Coakley, F. Simbari, H. J. McSorley, J. F. Quintana, T. Le Bihan, S. Kumar, C. Abreu-Goodger, M. Lear, Y. Harcus, A. Ceroni, S. A. Babayan, M. Blaxter, A. Ivens and R. M. Maizels (2015). ‘Erratum: Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.’ Nat Commun 6: 8772.

Christensen, L. L., C. Selman, J. D. Blount, J. G. Pilkington, K. A. Watt, J. M. Pemberton, J. M. Reid and D. H. Nussey (2015). ‘Plasma markers of oxidative stress are uncorrelated in a wild mammal.’ Ecol Evol 5(21): 5096-5108.

Coakley, G., R. M. Maizels and A. H. Buck (2015). ‘Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections.’ Trends Parasitol 31(10): 477-489.

Glintborg, D., L. L. Christensen, T. Kvorning, R. Larsen, K. Hojlund, K. Brixen, D. M. Hougaard, A. Handberg and M. Andersen (2015). ‘Differential effects of strength training and testosterone treatment on soluble CD36 in aging men: Possible relation to changes in body composition.’ Scand J Clin Lab Invest 75(8): 659-666.

Huesa, C., D. Houston, T. Kiffer-Moreira, M. M. Yadav, J. L. Millan and C. Farquharson (2015). ‘The Functional co-operativity of Tissue-Nonspecific Alkaline Phosphatase (TNAP) and PHOSPHO1 during initiation of Skeletal Mineralization.’ Biochem Biophys Rep 4: 196-201.

Javaheri, B., A. Carriero, K. A. Staines, Y. M. Chang, D. A. Houston, K. J. Oldknow, J. L. Millan, B. N. Kazeruni, P. Salmon, S. Shefelbine, C. Farquharson and A. A. Pitsillides (2015). ‘Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing.’ Bone 81: 277-291.

Johnston, C. J., E. Robertson, Y. Harcus, J. R. Grainger, G. Coakley, D. J. Smyth, H. J. McSorley and R. Maizels (2015). ‘Cultivation of Heligmosomoides polygyrus: an immunomodulatory nematode parasite and its secreted products.’ J Vis Exp(98): e52412.

Luo, X., G. McGregor, A. J. Irving and J. Harvey (2015). ‘Leptin Induces a Novel Form of NMDA Receptor-Dependent LTP at Hippocampal Temporoammonic-CA1 Synapses(1,2,3).’ eNeuro 2(3).

Mabbott, N. A., A. Kobayashi, A. Sehgal, B. M. Bradford, M. Pattison and D. S. Donaldson (2015). ‘Aging and the mucosal immune system in the intestine.’ Biogerontology 16(2): 133-145.

McGregor, G., Y. Malekizadeh and J. Harvey (2015). ‘Minireview: Food for thought: regulation of synaptic function by metabolic hormones.’ Mol Endocrinol 29(1): 3-13.

Smith, S., C. Cianci and R. Grima (2015). ‘Model reduction for stochastic chemical systems with abundant species.’ J Chem Phys 143(21): 214105.

Zhang, H. Y., L. Picton, W. C. Li and K. T. Sillar (2015). ‘Mechanisms underlying the activity-dependent regulation of locomotor network performance by the Na+ pump.’ Sci Rep 5: 16188.

Zhang, R., C. P. Calixto, N. A. Tzioutziou, A. B. James, C. G. Simpson, W. Guo, Y. Marquez, M. Kalyna, R. Patro, E. Eyras, A. Barta, H. G. Nimmo and J. W. Brown (2015). ‘AtRTD - a comprehensive reference transcript dataset resource for accurate quantification of transcript-specific expression in Arabidopsis thaliana.’ New Phytol 208(1): 96-101.


Adam, C. L., P. A. Williams, M. J. Dalby, K. Garden, L. M. Thomson, A. J. Richardson, S. W. Gratz and A. W. Ross (2014). ‘Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats.’ Nutr Metab (Lond) 11: 36.

Buck, A. H., G. Coakley, F. Simbari, H. J. McSorley, J. F. Quintana, T. Le Bihan, S. Kumar, C. Abreu-Goodger, M. Lear, Y. Harcus, A. Ceroni, S. A. Babayan, M. Blaxter, A. Ivens and R. M. Maizels (2014). ‘Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.’ Nat Commun 5: 5488.

Gorgoni, B., E. Marshall, M. R. McFarland, M. C. Romano and I. Stansfield (2014). ‘Controlling translation elongation efficiency: tRNA regulation of ribosome flux on the mRNA.’ Biochem Soc Trans 42(1): 160-165.

Gow, D. J., K. A. Sauter, C. Pridans, L. Moffat, A. Sehgal, B. M. Stutchfield, S. Raza, P. M. Beard, Y. T. Tsai, G. Bainbridge, P. L. Boner, G. Fici, D. Garcia-Tapia, R. A. Martin, T. Oliphant, J. A. Shelly, R. Tiwari, T. L. Wilson, L. B. Smith, N. A. Mabbott and D. A. Hume (2014). ‘Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor.’ Mol Ther 22(9): 1580-1592.

Kneuper, H., Z. P. Cao, K. B. Twomey, M. Zoltner, F. Jager, J. S. Cargill, J. Chalmers, M. M. van der Kooi-Pol, J. M. van Dijl, R. P. Ryan, W. N. Hunter and T. Palmer (2014). ‘Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains.’ Mol Microbiol 93(5): 928-943.

Lewicka, A. J., J. J. Lyczakowski, G. Blackhurst, C. Pashkuleva, K. Rothschild-Mancinelli, D. Tautvaisas, H. Thornton, H. Villanueva, W. Xiao, J. Slikas, L. Horsfall, A. Elfick and C. French (2014). ‘Fusion of pyruvate decarboxylase and alcohol dehydrogenase increases ethanol production in Escherichia coli.’ ACS Synth Biol 3(12): 976-978.

Sauter, K. A., C. Pridans, A. Sehgal, C. C. Bain, C. Scott, L. Moffat, R. Rojo, B. M. Stutchfield, C. L. Davies, D. S. Donaldson, K. Renault, B. W. McColl, A. M. Mowat, A. Serrels, M. C. Frame, N. A. Mabbott and D. A. Hume (2014). ‘The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration.’ PLoS One 9(8): e105429.

Sauter, K. A., C. Pridans, A. Sehgal, Y. T. Tsai, B. M. Bradford, S. Raza, L. Moffat, D. J. Gow, P. M. Beard, N. A. Mabbott, L. B. Smith and D. A. Hume (2014). ‘Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.’ J Leukoc Biol 96(2): 265-274.

Download the list of publications here.