Winning in western blotting at Thermo Fisher Scientific (please click on the title to read more)
by Zandile Nare
I am a second-year EASTBIO PhD student within the Institute of Immunology and Infection Research at the University of Edinburgh. My research focuses on the identification of specific inhibitors of kinetoplastid RNA editing ligase 1 (REL1), a validated drug target, for use as lead compounds for the treatment of human and animal diseases caused by kinetoplastid parasites (e.g. sleeping sickness, nagana, Chagas disease & various leishmaniases). A secondary goal of my PhD is to understand structure-activity relationships of REL1 and the other kinetoplastid ligase; REL2.
PIPS project background and motivation for pursuing project