Current News

15 Mar 2018

Winning in western blotting at Thermo Fisher Scientific (please click on the title to read more)
by Zandile Nare

Background information

I am a second-year EASTBIO PhD student within the Institute of Immunology and Infection Research at the University of Edinburgh. My research focuses on the identification of specific inhibitors of kinetoplastid RNA editing ligase 1 (REL1), a validated drug target, for use as lead compounds for the treatment of human and animal diseases caused by  kinetoplastid parasites (e.g. sleeping sickness, nagana, Chagas disease & various leishmaniases). A secondary goal of my PhD is to understand structure-activity relationships of REL1 and the other kinetoplastid ligase; REL2.

PIPS project background and motivation for pursuing project

27 Feb 2018

David Walker, fourth-year EASTBIO student at the University of St Andrews (his project is 'Stress on the brain: Implications for cognitive ageing'), along with his MSc supervisor Dr Stephen Land, identified a new role for the protein, Sprouty2, a known regulator of airway branching during embryonic lung development. They found that this protein also acts within the nucleus of lung epithelial cells to regulates vascular growth of the developing lung. They conclude that nuclear Spry2 acts as a molecular link which co-ordinates airway and vascular growth of the cardiopulmonary system.

You can find the link to David's paper here.

20 Feb 2018

Stevie Bain, final year EASTBIO PhD student at the University of Edinburgh, was invited by Springer nature group to blog on her research. Stevie works on Parental Genome Elimination (PGE), a unique type of genomic imprinting.

Her resulting blog - "Paternal genome elimination: investigating a strange reproductive strategy" - can be found here.