Genomic comparisons of trypanosomatid veterinary vaccine vehicles optimised for different target species
Time to hatch and feed: Neuroendocrine mechanisms underpinning behaviour in avian early life
Supervisors: Professor Simone Meddle, Professor Sue Healy
Project Description:
Using novel drug discovery platforms to inhibit ENPP enzymes during the calcification process
Supervisors: Scott Webster, Vicky MacRae, Patrick Hadoke
Project Description:
Heart disease and strokes affect about one person in three and are in part caused by arteries and valves becoming stiffened with calcium deposits (1). However, how this vascular calcification occurs is not fully known.
Definition and validation of the epigenetic landscape of avian craniofacial morphogenesis
Supervisors: Jeffrey J. Schoenebeck, Megan Davey
Project Description:
The study of chicken embryogenesis was and remains essential to our understanding of vertebrate developmental biology. Unlike placental mammals, chick embryos are easily accessed, manipulated, and studied live in ovo.
Characterising how the HUSH complex can induce the epigenetic repression of retroviruses and retroelements
Supervisors: Richard Sloan, Jose Garcia-Perez
Project Description:
Computational analysis of single cell RNA-seq data to identify signalling networks underpinning tissue specific macrophage function during development and pathology
Supervisors: Nizar Batada, Veronique Miron, Stephen Jenkins
Project Description:
Determining the role of new molecules in activity-dependent bulk endocytosis
Supervisors: Michael Cousin, Karen Smillie
Project Description:
The role of TRIM25/RNA interactions in innate immune response to influenza A infection
Supervisors: Dr Gracjan Michlewski, Dr Sander Granneman
Project Description:
Engrams and neural circuitry for episodic memory
Supervisors: Matthew Nolan, James Ainge
Project Description: