Protein kinase regulation of cell polarity: a phosphoproteomics approach

Supervisors: Prof Kenneth Sawin, Dr Tony Ly

Project Description:

Nearly all eukaryotic cells are polarised—they have an internal architecture and/or external (i.e. cell surface) organisation that gives them a front and a back, a top and a bottom, or proximal and distal regions. Cell polarity enables specific functions such as cell growth, migration, asymmetric division (e.g. stem cells), and orientation within tissues.