Projects

Targeting transient protein states for the design of chemical probes of Cyclophilins function

Supervisors: Julien Michel, Malcolm Walkinshaw, Alison Hulme

Project description:

The main objective of this project is to contribute to the development of novel chemical probes of Cyclophilins function using a range of state-of the art methodologies from chemical, structural and computational biology.

Other: 

The role of the Rab32/BLOC3 host defence pathway in controlling Staphylococcus aureus infections

Supervisors: Massimiliano Baldassarre, Stefania Spanò, Ross J Fitzgerald

Project description:

S. aureus is an emerging problem in animal agriculture and veterinary medicine and our recent studies have shown how livestock could represent a source of pathogenic S. aureus (1) with the potential to spread in human populations.

Other: 

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